Aminophylline for Dogs

Veterinarians frequently prescribe aminophylline for dogs suffering from asthma or bronchitis even though it is not currently approved by the FDA for use in animals. Aminophylline belongs to a class of drugs called bronchodilators, used to relax the smooth muscle wall in the airway and allowing unrestricted air passage.

Dosage for Dogs

Aminophylline is available by prescription for dogs. It is available in tablets, oral liquid, injection and suppository form. Typical dosage is 3 to 5 mg per pound every 8 hours.

Side Effects of Aminophylline for Dogs

A dog on aminophylline can experience side effects such as vomiting, diarrhea, anxiety or nervousness, insomnia, or increased hunger, thirst and urination. Side effects may subside with continued therapy or may require dosage adjustments.


  • Caution should be used when giving aminophylline to dogs with seizure disorders. Medications used to treat seizures can lessen the effectiveness of this drug.
  • Animals with hypothyroidism, liver or kidney disease or congestive heart failure should use aminophylline with caution as it can cause problems with these conditions.
  • Aminophylline should not be given to dogs that are pregnant or nursing or to dogs who are allergic to this class of medication.
  • Although not approved by the FDA for use in dogs, aminophylline can be used with care in the treatment of canine asthma and bronchitis. As with other prescription medications, dosing instructions should be followed carefully.