Anipryl Side Effects

Learn all possible side effects of Anipryl. Part of the L-Deprenyl Hydrochloride, also called Selegiline Hydrochloride, family of prescription medications, Anipryl is used to treat Canine Cognitive Dysfunction (CCD) and certain forms of Cushing's Disease. Many pet owners associate canine arthritis as the biggest hurdle their elderly dog may face, but Cushing's Disease and CCD are very common in older dogs.

L-Deprenyl Hydrochloride drugs include:

L-Deprenyl medications inhibit the production of ACTH, a hormone produced by the pituitary gland that triggers the adrenal glands to produce too much cortisone.

Expect it to take a full month before you see any improvement in your pet's health. It takes a few weeks for the medication to build up and begin altering the brain chemicals.

Cushing's Disease and Syndrome Explained

Cushing's Disease and Cushing's Syndrome occur when there is too much cortisone in the bloodstream. Often, tumors of the pituitary gland or adrenal gland stimulate production, but overuse of steroids in dogs with canine arthritis or other painful conditions also causes Cushing's.

Dogs with Cushing's require medications or surgeries to remove tumors in order to prevent the overproduction of cortisol. Selegiline Hydrochloride drugs are usually the preferred treatment.

Canine Cognitive Dysfunction Syndrome Explained

As a dog ages, brain function changes. For dogs with CDS, brain chemical changes develop a host of issues including disorientation, frequent accidents in the house, lack of energy and lack of interest or enthusiasm towards family members.

By using Selegiline Hydrochloride to help maintain brain chemical levels, pet owners regain a loving, interested pet.

Dosages of L-Deprenyl Hydrochloride Medications

L-Deprenyl Hydrochloride medications come in blister packs. The pills are taken orally and come in 2mg, 5mg, 10mg, 15mg and 30mg dosages. Your veterinarian will prescribe the best dosage for your pets weight.

If you forget to give your dog its pill, providing you've only missed the scheduled dosage by a few hours. If the next dose is within the next 16 hours, skip that missed dose. Never double the next dose.

Side Effects of Anipryl

Common side effects include:

  • Anemia

  • Diarrhea

  • Excessive drooling

  • Hearing loss

  • Itchy skin

  • Lack of appetite

  • Lethargy

  • Restlessness

  • Vomiting

Dangerous side effects, including allergic reactions, include:

  • Circulation issues

  • Coma

  • Facial swelling

  • Hives

  • Seizures

  • Shock

If your dog appears to be having an allergic reaction, seek emergency veterinary care immediately.

If your dog has overdosed on the medication, dehydration, excessive panting and weight loss are common. You may also see the dog's pupils failing to contract in bright light.

Contraindications for Anipryl

If you are using any Selegiline Hydrochloride drugs, you should be aware that the drug's safety has not been fully tested on nursing or pregnant animals.

Anipryl cannot be taken within five weeks of any antidepressants or SSRI medications. Also make sure the dog has not taken MAOIs within the past five weeks.

Never give your dog ephedrine while he is taking a Selegiline Hydrochloride. Do not use any flea or tick collars, shampoos or topical medications containing Amitraz or Mitaban.

Phenylpropanolamine is used to treat urinary incontinence in older dogs. If you mix phenylpropanolamine with Anipryl, dangerously high blood pressure levels may occur. It is highly recommended that you stop giving your dog phenylpropanolamine at least two weeks prior to using Selegiline Hydrochloride medications.