Controlling Chronic Osteoarthritis With Deramaxx

Deramaxx is a brand of deracoxib, a non-steroidal anti-inflammatory (NSAID) drug used to control symptoms associated with chronic canine osteoarthritis. As one of the most common degenerative diseases among dogs, osteoarthritis (OA) results from the progressive loss of cartilage in the joints. Cartilage is a connective tissue that provides a cushion to prevent bones from rubbing against each other during movement.

As cartilage deteriorates, dogs typically experience pain, swelling and stiffness in the joints, leading to impaired movement. While there is no cure for canine osteoporosis, the disease can be managed through medication. Deramaxx is frequently prescribed to help reduce the inflammation and control pain caused by the disease. Here is a description of how Deramaxx can help manage some of the most common and unpleasant symptoms of OA, along with guidelines and precautions regarding its use.

How Deramaxx Works

Deramaxx, like other NSAIDs, operates by blocking certain chemicals responsible for distributing pain signals when the body is ill or injured. In the case of osteoarthritis, cartilage breakdown due to injury, illness or unidentified factors, triggers a dog's immune system to release the protein cyclooxygenase (COX), which creates prostaglandins. These hormone-like substances help fight infection through natural process that often cause soreness, inflammation and fever. While these immunological responses are important to combating infection, they can also contribute to the chronic pain and uncomfortable swelling associated with OA. Deramxx is a newer form of NSAIDs called COX-2 inhibitors. These drugs limit the function of COX-2, one of three variations of the the COX enzyme. COX-2 is thought to have a primary role in the creation of the prostaglandins that cause pain and inflammation. By inhibiting the activity of COX-2, Deramaxx can help control soreness and manage swelling in dogs with OA.

Deramaxx Use and Side Effects

Deramaxx, manufactured by Novartis Animal Health, is a brand of the prescription NSAID deracoxib. It typically comes in 25 mg, 75 mg and 100 mg round brown tablets that are chewable and flavored for easier ingestion. Deramaxx is designed to work quickly throughout a 24-hour period. It can also be given along other non-NSAID painkillers, like Tramadol for dogs. Deramaxx is not recommended for dogs with allergies to deracoxib or other NSAIDs.

It is also not intended for use in dogs under the following conditions: pregnancy, current use of another NSAID, liver or kidney disorders, history of dehydration or appetite loss. Certain Deramaxx side effects may indicate an adverse reaction to the drug, such as decreased appetite, vomiting, increase or decrease of water intake, diarrhea, restlessness or lethargy. These may be signs of rare but serious reactions associated with the drug, like ulcers or liver, kidney or heart damage. Deramaxx is FDA-approved for use in dogs, however, owners may consider advising their veterinarian of any physical or behavioral changes their pet experiences after receiving the drug.

Witnessing the effects of canine osteoarthritis can be difficult for any dog owner. Although the problem is challenging, medications like Deramaxx may be an option for controlling the inflammation and swelling that accompany the degenerative disease. Learning about the benefits and risks of COX-2 inhibitors like Deramaxx is an important step for owners looking for ways to help manage their dog's osteoarthritis.