Dog Seizure Medication Comparison

Dog seizure medication is often necessary to treat the seizures associated with canine epilepsy. Here are some different types of dog seizure medication.


Phenobarbital is the most commonly prescribed dog seizure medication for epilepsy. It is relatively safe, effective, and inexpensive. There is some risk of liver damage associated with the use of phenobarbital. However, when used properly, the risk of liver damage caused by phenobarbital is low.

Potassium Bromide

Potassium bromide is the preferred dog seizure medication for dogs with idiopathic epilepsy. Potassium bromide has no effect on the liver, and is therefore ideal for dogs with liver damage.


Zonisamide is an effective dog seizure medication with few side effects, but it is expensive.


Felbamate can be used in conjunction with phenobarbital, but this increases the risk of liver damage, and so careful attention must be paid to the function of your dog's liver. Felbamate has few side effects, but it is expensive and requires frequent dosing.