Enrofloxacin Side Effects in Cats

Enrofloxacin is an antibiotic medication that belongs to the class of fluoroquinolones and may be used to treat infections. The drug is suitable for veterinary use only. In cats, the Enrofloxacin may be used to treat bacterial infections that affect the pet. The side effects of Enrofloxacin may include vomiting, diarrhea or even more severe negative effects such as seizures.

Enrofloxacin for Cats

Enrofloxacin can be used in cats, dogs, horses as well as other animals. Enrofloxacin is an antibiotic in the class of fluoroquinolone medications. The Enrofloxacin works by hindering the bacteria from reproducing and by killing the adult bacteria also.

The Enrofloxacin is only available through prescription and may be administered as a pill or as an injectable solution for more severe conditions.

Uses of Enrofloxacin

Enrofloxacin is often used in felines to treat several types of infections including:

  • Skin infections caused by bacteria
  • Respiratory infections
  • Urinary tract infections
  • Ear infections
  • Eye infections
  • Wound or scratch infections

The Enrofloxacin shouldn’t be used in viral, fungal or parasitic infections, as it is less likely to be effective. Enrofloxacin cannot be used to kill molds that may cause infections in felines.

Enrofloxacin Side Effects in Felines

Enrofloxacin may have side effects and the cat needs to be monitored to make sure these side effects won’t be severe or cause other complications.

Cats that are treated with Enrofloxacin may experience:

  • Nausea and vomiting
  • Diarrhea
  • Anxiety
  • Depression
  • Irritability and aggression
  • Lack of appetite followed by weight loss
  • Joint pain

In rare cases, the prolonged use of Enrofloxacin may cause severe behavioral changes and even seizures. Blindness may also be a rare side effect of the Enrofloxacin treatment.

In kittens and cats with undeveloped bones, the administration of Enrofloxacin may cause damage to the cartilages from the joints. Consequently, the medication shouldn’t be administered to young cats or kittens.

In blood tests, the use of Enrofloxacin may cause an increased level of liver enzymes.


The right dosage will be established by the vet, judging by the cat’s condition, weight and age. The Enrofloxacin should be administered once or twice daily until indicated by the vet (typically up to 14 days).

You should never give a higher dosage than indicated by the vet as it may be toxic in high doses.


Due to the fact that Enrofloxacin may cause cartilage damage in cats that are growing, the medication shouldn’t be used. Cats aged between 4 and 28 weeks should receive alternative treatment for bacterial infections.

Enrofloxacin shouldn’t be administered to cats that are allergic to it; felines with allergies to fluoroquinolones should also get a different treatment.

Enrofloxacin may interact with the administration of:

  • Iron supplements
  • Antacid drugs
  • Stomach padding medication

If mixed with these drugs, the side effects may be more severe.

To avoid side effects, you should discuss with the vet about alternative treatments and decide if the Enrofloxacin treatment is the most suitable.