Fluconazole is an oral antifungal antibiotic that’s administered to dogs with fungal infections such as ringworm, urinary infections or infections of the central nervous system. It is prescribed when other medications have proved to be ineffective against these infections.
Fluconazole for Pets
Fluconazole is a prescription medication that is recommended by veterinarians for the treatment of fungal infections. It is sold under the brand name Diflucan or Trican and is an oral medication that’s available in tablet and suspension form in various strengths. It is a synthetic triazole antifungal medication that can be administered with or without food and is completely absorbed by the dog’s body in 2 hours.
Action of Fluconazole
Fluconazole inhibits the activity of an enzyme known as demethylase that’s present in fungi but does not have the same effect on mammalian demethylase. As a result of the inhibition of this enzyme, fungi can’t synthesize ergosterol, an essential component of the fungal cell wall. Fluconazole thus, acts as a fungicide without harming the cells of your pet.
Side Effects of Fluconazole
Fluconazole side effects in dogs include:
- Loss of appetite
- Vomiting
- Diarrhea
- Jaundice
- Depression
- Rash
- Fatigue
- Renal failure
- Anemia
Indications of an Allergic Reaction to Fluconazole
If your pet has an allergic reaction to Fluconazole, he will develop a rash and have symptoms such as itchiness, hives, shock, facial swelling, vomiting, diarrhea and even coma. A veterinarian should be contacted at the earliest if your pet has any of these symptoms.
Dosage of Fluconazole
Fluconazole should be given as prescribed by the veterinarian. It may be necessary to administer the medication once or twice a day depending on the severity of the infection. It is essential that you do not miss a dose as it can lessen the efficacy of the medication. Hence, the exact amount should be given and it’s advisable to give the medication at the same time each day.
Fungal infections are very persistent and difficult to treat. Fluconazole takes 1 or 2 weeks to be effective and needs to be given for a few months to successfully overcome the infection.
If a dose is missed, you should give it as soon as you can unless it is time for the next dose, in which case it’s best not to give the missed dose in order to prevent an overdose. You should also contact the veterinarian if your pet takes more than the prescribed dose.
Contraindications You Should Keep in Mind
Fluconazole should not be given to pregnant or nursing dogs or to a pet that you plan to breed. Dogs with kidney or liver disease should also not be administered this medication unless the veterinarian feels that the benefits outweigh the risks.
You should advise the veterinarian of any allergies or medical problems suffered by your pet. Also inform the vet about all other medications and supplements that are being administered to your dog to ensure that there are no adverse interactions with other medications.
How You Should Store Fluconazole
Fluconazole should be stored in a tight container out of the reach of children and pets. It should be kept in a dry place away from heat and light and should not be used after the expiry date.
Although Fluconazole is more expensive than other medications such as griseofulvin, it is preferred over them as it is safer and has fewer side effects.