Over-the-Counter Dog Medicine for Canine Skin Conditions

Dog medicine is available as both prescription medications that should be administered after vet consultation and over the counter drugs that don't require prescriptions. Although over the counter drugs are considered safe to treat minor conditions, it's best to determine the cause of symptoms and use medicines that suit individual health concerns. Over the counter drugs are available to treat several dog skin and coat conditions. A few medicines are commercially available as topical solutions, while others are oral drugs that control skin infections.

Causes of Skin Infections in Dogs

Since there are various causes of skin conditions in dogs, the medication used to treat specific concerns differs. Bacterial infections, eczema, alopecia, mange, atopy and skin lesions are the most common types of skin conditions seen in dogs. It's advisable to conduct a vet check on pets suffering from itching skin, scales or crusty skin, skin thickening and sores. During clinical diagnosis, the vet will determine the type of skin condition present and rule out underlying health concerns or more serious illnesses such as lymphoma or sarcoma.

Over the Counter Medicine for Canine Skin Conditions:

  • Dermagard Hydrocortisone Medicated Spray
  • Homeo Pet Hot Spots
  • Clemastine
  • Diphenhydramine (Generic Benadryl)
  • Epi Soothe Oatmeal Cream Rinse
  • Clotrimazole

Dermagard Hydrocortisone Medicated Spray

This spray contains the active ingredient hydrocortisone hemi succinate and is used to treat itchy skin, inflammation and skin burning. Although the product is safe for use in dogs, it shouldn't come in contact with the pet's eyes.

Homeo Pet Hot Spots

Homeo Pet effectively treats skin rash, eczema and hot spots. Due to its organic nature, the medicine is safe and effective for use if administered according to the package instructions.


This is an antihistamine drug that reduces symptoms of skin allergy. It contains the active ingredient clemastine fumarate. Although it does cause few side effects, it provides prompt and temporary relief from allergic reactions. Clemastine may not be safe for dogs suffering from cardiac problems and bladder disorders. It's best to discuss with the vet if clemastine is safe for individual pets.


This medication is available as minitabs and capsules of varying potencies. It's used to treat skin conditions such as allergies and insect bites. Since it's an antihistamine drug, it's not safe for use in dogs suffering from urinary problems, blood pressure and pregnant pets.

Epi Soothe Oatmeal Cream Rinse

Epi Soothe cream rinse benefits dogs suffering from dry skin, matted hair and rough sensitive skin. It contains a blend of ingredients that are safe for use in most pets. Pet owners should prevent the solution from coming in contact with the dog's eyes.


Clotrimazole effectively treats fungal skin infections and skin conditions caused by ringworm. If the pet develops severe side effects such as hives or blisters, it's best to seek medical help. Pets that don't respond to clotrimazole treatment require further diagnostic tests and prescribed medication.

Pet owners should read and follow package instructions during administration of over the counter dog medicines. If the conditions persist even after treatment, it's best to seek vet assistance. Dogs suffering from frequent skin conditions should be kept in a clean environment free from toxic substances, pollen, smoke and dust.